Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543881 | 0.81 | SLC6A2 (0.39) | LMNASLC6A2TP53ICMTSLC6A3 | |
| SCHEMBL754463 | 0.76 | SLC6A3 (0.41) | LMNASLC6A2ICMTSLC6A3OPRM1 | |
| SCHEMBL2208999 | 0.76 | SLC6A2 (0.35) | SLC6A2TP53ICMTSLC6A3OPRM1 | |
| SCHEMBL10779269 | 0.74 | ICMT (0.33) | SLC6A2ICMTSLC6A3SLC6A4MEN1 | |
| SCHEMBL28983665 | 0.71 | ICMT (0.46) | LMNATSHRSLC6A2TP53ICMT | |
| SCHEMBL10779346 | 0.70 | HSD17B10 (0.39) | LMNATSHRTP53MEN1KMT2A | |
| SCHEMBL11548284 | 0.70 | HSP90AA1 (0.39) | MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL27487819 | 0.69 | — | — | |
| SCHEMBL10783718 | 0.69 | USP2 (0.35) | LMNATSHRTP53 | |
| SCHEMBL14779113 | 0.68 | TSHR (0.47) | TSHRMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1214022-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2005-08-10 | — | — | CN | disclosed |
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| CN-1423645-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2003-06-11 | — | — | CN | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |