Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564460 | 0.89 | ACACB (0.51) | ACACBF10PRSS1HPGDMEN1 | |
| SCHEMBL6563427 | 0.86 | ACACB (0.49) | ACACBALDH1A1HPGDMEN1LMNA | |
| SCHEMBL6563675 | 0.80 | F10 (0.47) | ACACBF10PRSS1ALDH1A1HPGD | |
| SCHEMBL7677322 | 0.79 | ALDH1A1 (0.44) | F10PRSS1ALDH1A1HPGDITGB3 | |
| SCHEMBL5885506 | 0.79 | ACACB (0.48) | ACACBF10PRSS1ALDH1A1HPGD | |
| SCHEMBL6563450 | 0.79 | F10 (0.48) | ACACBF10PRSS1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5885815 | 0.78 | ACACB (0.47) | ACACBF10PRSS1ALDH1A1HPGD | |
| SCHEMBL6565941 | 0.77 | F10 (0.47) | ACACBF10PRSS1ALDH1A1HPGD | |
| SCHEMBL24065200 | 0.76 | HPGD (0.70) | ALDH1A1HPGDITGB3ITGA2BMEN1 | |
| SCHEMBL6563505 | 0.74 | ACACB (0.53) | ACACBF10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |