Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | F7 | P08709 | 6/20 | 0.36 |
| ▸ | F3 | P13726 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 12/20 | 0.35 |
| ▸ | F10 | P00742 | 9/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563059 | 0.89 | NQO2 (0.41) | NQO2ITGB3ITGA2BF7F3 | |
| SCHEMBL6565414 | 0.86 | PTPN11 (0.33) | NQO2 | |
| SCHEMBL6563366 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BF7F3F2 | |
| SCHEMBL7675036 | 0.81 | F10 (0.42) | ITGB3ITGA2BF7F3F2 | |
| SCHEMBL6565349 | 0.80 | F2 (0.38) | F7F3F2F10PLAU | |
| SCHEMBL6563588 | 0.78 | F2 (0.41) | F7F3F2F10PLAU | |
| SCHEMBL6563363 | 0.77 | F2 (0.38) | ITGB3ITGA2BF7F3F2 | |
| SCHEMBL7675157 | 0.76 | ITGB3 (0.36) | NQO2ITGB3ITGA2BF7F3 | |
| SCHEMBL6565505 | 0.76 | MTOR (0.36) | F7F3F2F10PLAU | |
| SCHEMBL6563647 | 0.76 | F7 (0.36) | ITGB3ITGA2BF7F3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |