Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279952 | 0.82 | ALDH1A1 (0.37) | BRD4TRIM24TRIM33DRD2DRD1 | |
| SCHEMBL6564846 | 0.80 | PRKDC (0.38) | NPY5RPRKDC | |
| SCHEMBL2025223 | 0.69 | BRD4 (0.43) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL2911266 | 0.69 | ESR2 (0.59) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL16726969 | 0.69 | BRD4 (0.43) | BRD4TRIM24TRIM33NPY5RCA12 | |
| SCHEMBL3479559 | 0.68 | BRD4 (0.47) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL26704142 | 0.67 | SLC1A3 (0.45) | BRD4TRIM24TRIM33CA12CA1 | |
| SCHEMBL13593734 | 0.67 | CHRNA1 (0.41) | — | |
| SCHEMBL2561660 | 0.66 | TRIM24 (0.63) | BRD4TRIM24TRIM33 | |
| SCHEMBL6062294 | 0.66 | EGLN2 (0.41) | BRD4TRIM24TRIM33CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |