Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | UNG | P13051 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875142 | 0.83 | L3MBTL1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL6564844 | 0.82 | BRD4 (0.37) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL856168 | 0.79 | ALDH1A1 (0.40) | ALDH1A1UNGMAOAMAOBBRD4 | |
| SCHEMBL13593734 | 0.77 | CHRNA1 (0.41) | — | |
| SCHEMBL3283931 | 0.76 | PTPN1 (0.41) | — | |
| SCHEMBL3280576 | 0.76 | CHRNA1 (0.41) | ALDH1A1 | |
| SCHEMBL3127971 | 0.75 | ALDH1A1 (0.37) | ALDH1A1UNGMAOAMAOBBRD4 | |
| SCHEMBL14779113 | 0.74 | TSHR (0.47) | ALDH1A1TDP1 | |
| SCHEMBL309992 | 0.69 | ALDH1A1 (0.44) | ALDH1A1UNGMAOAMAOBBRD4 | |
| SCHEMBL3652080 | 0.69 | ALDH1A1 (0.40) | ALDH1A1UNGMAOAMAOBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| EP-1395538-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2009-12-30 | — | — | EP | disclosed |
| CN-1267394-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2006-08-02 | — | — | CN | disclosed |
| CN-1549803-A | Vitamin D analogues | �������о�����չ˽������˾ | 2004-11-24 | — | — | CN | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1395538-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094754-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2002-11-28 | — | — | WO | disclosed |