SCHEMBL6564864

SCHEMBL6564864

C=Cc1ccc(OC2CCCO2)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 3/20 0.37
PTPN1 P18031 2/20 0.33
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
GCGR P47871 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562646 0.96 PTPN1 (0.37) PDE4BPTPN1KDM4CGCGR
SCHEMBL29869547 0.96 PTPN1 (0.37) PDE4BPTPN1KDM4CGCGR
SCHEMBL8111504 0.82 PDE4B (0.36) PDE4BPTPN1KDM4EKDM4C
SCHEMBL6362992 0.82 KDM4C (0.42) PDE4BPTPN1KDM4ETSHRKDM4C
SCHEMBL1355137 0.78 PTPN1 (0.39) PDE4BPTPN1KDM4EKDM4C
SCHEMBL10745665 0.75 PDE4B (0.46) PDE4BPTPN1KDM4ETSHRKDM4C
SCHEMBL3873875 0.74 PDE4B (0.36) PDE4BKDM4ETSHRKDM4CPDE4A
SCHEMBL8528712 0.72 PDE4B (0.50) PDE4BPTPN1KDM4EPDE4APDE4C
SCHEMBL21339739 0.72 PTPN1 (0.39) PDE4BPTPN1KDM4C
SCHEMBL11057549 0.71 KDM4C (0.44) KDM4EKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed