Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564885 | 1.00 | MRGPRX4 (0.34) | MRGPRX4CYP4F2CYP4A11MAOBTP53 | |
| SCHEMBL6886891 | 0.90 | MRGPRX4 (0.32) | MRGPRX4CYP4F2CYP4A11MAOBSMN1; SMN2 | |
| SCHEMBL6886887 | 0.90 | MRGPRX4 (0.32) | MRGPRX4CYP4F2CYP4A11MAOBSMN1; SMN2 | |
| SCHEMBL6562874 | 0.87 | CYP4F2 (0.34) | MRGPRX4CYP4F2CYP4A11MAOBTP53 | |
| SCHEMBL6562882 | 0.87 | CYP4F2 (0.34) | MRGPRX4CYP4F2CYP4A11MAOBTP53 | |
| SCHEMBL6564880 | 0.84 | MAOB (0.32) | MAOBMAOAMAPTHTTL3MBTL1 | |
| SCHEMBL6564886 | 0.84 | MAOB (0.32) | MAOBMAOAMAPTHTTL3MBTL1 | |
| SCHEMBL6564155 | 0.80 | MRGPRX4 (0.39) | MRGPRX4TP53MAPTL3MBTL1 | |
| SCHEMBL6564148 | 0.80 | MRGPRX4 (0.39) | MRGPRX4TP53MAPTL3MBTL1 | |
| SCHEMBL6566186 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |