SCHEMBL6564901

SCHEMBL6564901

CC(C)SCCC(N)C(O)C(=O)NNC(=O)c1cccc(SCC(C)(C)C)c1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 20/20 0.69
METAP1 P53582 14/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6477446 1.00 METAP2 (0.69) METAP2METAP1
SCHEMBL6485509 0.89 METAP2 (0.76) METAP2METAP1
SCHEMBL6478204 0.89 METAP2 (0.76) METAP2METAP1
SCHEMBL6488317 0.88 METAP2 (0.71) METAP2METAP1
SCHEMBL6477853 0.88 METAP2 (0.71) METAP2METAP1
SCHEMBL6486021 0.88 METAP2 (0.62) METAP2METAP1
SCHEMBL6477449 0.87 METAP2 (0.76) METAP2METAP1
SCHEMBL6563406 0.86 METAP2 (0.69) METAP2METAP1
SCHEMBL6487333 0.86 METAP2 (0.69) METAP2METAP1
SCHEMBL6477200 0.86 METAP2 (0.68) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1272456-B1 HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS ABBOTT LAB (US) 2004-10-27 EP claimed