Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564787 | 1.00 | HPGD (0.56) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6564878 | 0.97 | HPGD (0.58) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL14802012 | 0.83 | MAPK1 (0.63) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6566970 | 0.83 | HTT (0.44) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6565781 | 0.83 | HTT (0.44) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13162930 | 0.81 | NPC1 (0.60) | HPGDHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL13637521 | 0.81 | HPGD (0.53) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL1063005 | 0.80 | TSHR (0.66) | HPGDHTTTSHRALDH1A1KDM4E | |
| SCHEMBL27100324 | 0.79 | TSHR (0.57) | HPGDHTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6903284 | 0.79 | TSHR (0.58) | HPGDHTTTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854177-B1 | Ink compositions | XEROX CORP (US) | 2004-03-31 | — | — | EP | disclosed |