Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564878 | 0.86 | HPGD (0.58) | MAPK1HPGDALDH1A1TSHRHTT | |
| SCHEMBL6903284 | 0.86 | TSHR (0.58) | HPGDALDH1A1TSHRHTTHSD17B10 | |
| SCHEMBL3205212 | 0.84 | MAPK1 (0.47) | MAPK1HPGDALDH1A1ALOX15GAA | |
| SCHEMBL30223440 | 0.83 | ALDH1A1 (0.68) | MAPK1HPGDALDH1A1ALOX15GAA | |
| SCHEMBL21780290 | 0.83 | MAPK1 (0.51) | MAPK1HPGDALDH1A1ALOX15GAA | |
| SCHEMBL2546081 | 0.83 | ALDH1A1 (0.68) | MAPK1HPGDALDH1A1ALOX15GAA | |
| SCHEMBL6564787 | 0.83 | HPGD (0.56) | MAPK1HPGDALDH1A1TSHRHTT | |
| SCHEMBL6564965 | 0.83 | HPGD (0.56) | MAPK1HPGDALDH1A1TSHRHTT | |
| SCHEMBL1063005 | 0.83 | TSHR (0.66) | HPGDALDH1A1GAATSHRHTT | |
| SCHEMBL13161949 | 0.81 | HPGD (0.65) | MAPK1HPGDALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130074864-A1 | AIRBRUSH | L'OREAL (FR) | 2013-03-28 | — | — | US | disclosed |