SCHEMBL6903284

SCHEMBL6903284

NC(=O)c1ccccc1C(=O)NCCNC(=O)c1ccccc1C(N)=O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
HTT P42858 1/20 0.58
HCRTR1 O43613 1/20 0.51
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
HPGD P15428 3/20 0.48
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48
HSD17B10 Q99714 1/20 0.48
APEX1 P27695 1/20 0.47
LMNA P02545 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29067150 0.91 TSHR (0.54) TSHRHTTHCRTR1KMT2AMEN1
SCHEMBL9570919 0.90 ALDH1A1 (0.54) TSHRHTTHCRTR1KMT2AMEN1
SCHEMBL8652703 0.90 TSHR (0.53) TSHRHTTHCRTR1KMT2AMEN1
SCHEMBL9516588 0.89 TSHR (0.51) TSHRHTTHCRTR1KMT2AHPGD
SCHEMBL2080518 0.89 TSHR (0.51) TSHRHTTHCRTR1KMT2AHPGD
SCHEMBL1063005 0.89 TSHR (0.66) TSHRHTTHCRTR1HPGDKDM4E
SCHEMBL7255678 0.87 HTT (0.62) TSHRHTTHCRTR1HPGDKDM4E
SCHEMBL2129167 0.86 TSHR (0.47) TSHRHTTKMT2AHPGDKDM4E
SCHEMBL14802012 0.86 MAPK1 (0.63) TSHRHTTKMT2AMEN1HPGD
SCHEMBL9518458 0.86 HTT (0.57) TSHRHTTHCRTR1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401879-A1 RANDOM OR BLOCK CO-OR TERPOLYMERS PRODUCED BY USING OF METAL COMPLEX CATALYSTS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-03-31 EP disclosed
WO-2002090394-A1 RANDOM OR BLOCK CO-OR TERPOLYMERS PRODUCED BY USING OF METAL COMPLEX CATALYSTS DOW GLOBAL TECHNOLOGIES INC. (US) 2002-11-14 WO disclosed