SCHEMBL6565149

SCHEMBL6565149

COc1[c]c(-c2[c]cccc2)ccc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11973102 0.79
SCHEMBL147429 0.78 LTA4H (0.38) KDM4E
SCHEMBL7100899 0.77
SCHEMBL1413 0.77
SCHEMBL10395477 0.77 ALDH1A1 (0.42) KDM4EALDH1A1MAPK1SMN1; SMN2CA12
SCHEMBL15067316 0.76 LTA4H (0.38) KDM4EALDH1A1SMN1; SMN2
SCHEMBL336435 0.76 PDE4B (0.38) KDM4EALDH1A1MAPK1SMN1; SMN2CA12
SCHEMBL25337663 0.74
SCHEMBL28313311 0.74
SCHEMBL10702137 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401974-A1 WATERBORNE COATING COMPOSITION AND PROCESS OF PRODUCING A FILM HAVING A IMPROVED ADHESION ON A SUBSTRATE Basf Corporation (US) 2004-03-31 EP disclosed
US-20030008079-A1 Waterborne coating compostion and process of producing a film having improved adhesion on a substrate BASF CORPORATION 2003-01-09 US disclosed
WO-2002094956-A1 WATERBORNE COATING COMPOSITION AND PROCESS OF PRODUCING A FILM HAVING A IMPROVED ADHESION ON A SUBSTRATE BASF CORPORATION (US) 2002-11-28 WO disclosed