Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564505 | 0.77 | VDR (0.38) | CD274PDCD1VDR | |
| SCHEMBL6564946 | 0.76 | VDR (0.39) | CD274PDCD1VDR | |
| SCHEMBL6565120 | 0.75 | VDR (0.38) | CD274PDCD1VDR | |
| SCHEMBL6564892 | 0.74 | VDR (0.38) | CD274PDCD1VDR | |
| SCHEMBL6564955 | 0.69 | VDR (0.38) | CD274PDCD1VDR | |
| SCHEMBL6562827 | 0.67 | VDR (0.35) | CD274PDCD1VDR | |
| SCHEMBL6564896 | 0.67 | VDR (0.34) | CD274PDCD1VDR | |
| SCHEMBL6564984 | 0.66 | VDR (0.39) | VDR | |
| SCHEMBL6564908 | 0.65 | VDR (0.38) | VDR | |
| SCHEMBL16245269 | 0.61 | PDCD1 (0.76) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |