Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564550 | 0.89 | VDR (0.39) | VDRMAOBPDK2PDK1PDK3 | |
| SCHEMBL6564946 | 0.85 | VDR (0.39) | VDRCD274PDCD1 | |
| SCHEMBL6562827 | 0.84 | VDR (0.35) | VDRPDK2CD274PDCD1HDAC6 | |
| SCHEMBL6564896 | 0.83 | VDR (0.34) | VDRPDK2CD274PDCD1HDAC6 | |
| SCHEMBL6564961 | 0.80 | VDR (0.38) | VDRMAOBPDK2FFAR1PRKD3 | |
| SCHEMBL6889710 | 0.79 | VDR (0.41) | VDRMAOBPDK2PDK1PDK3 | |
| SCHEMBL6564553 | 0.77 | VDR (0.39) | VDRMAOBPDK2PDK1PDK3 | |
| SCHEMBL6564512 | 0.75 | VDR (0.35) | VDRPDK2 | |
| SCHEMBL6564505 | 0.74 | VDR (0.38) | VDRCD274PDCD1 | |
| SCHEMBL6564984 | 0.74 | VDR (0.39) | VDRPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |