SCHEMBL3347146

SCHEMBL3347146

CCCCN(CC(=O)O)c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.47
EGFR P00533 1/20 0.46
ERBB2 P04626 1/20 0.46
PLA2G2A P14555 1/20 0.42
BLM P54132 1/20 0.42
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 2/20 0.41
CNR1 P21554 1/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KCNH2 Q12809 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
CCKBR P32239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3349327 0.90 CNR2 (0.43) CNR2EGFRERBB2CNR1GAA
SCHEMBL3347562 0.85 KEAP1 (0.46) CNR2EGFRERBB2PLA2G2ABLM
SCHEMBL3342781 0.85 CNR2 (0.48) CNR2PLA2G2ABLMNR1H2NR1H3
SCHEMBL3341126 0.84 EGFR (0.42) CNR2EGFRERBB2PLA2G2ABLM
SCHEMBL1633085 0.83 CNR2 (0.51) CNR2CNR1GAAMEN1MAPT
SCHEMBL342249 0.82 ALDH1A1 (0.44) CNR2BLMMEN1MAPTKMT2A
SCHEMBL6565246 0.82 EGFR (0.47) CNR2EGFRERBB2NR1H2NR1H3
SCHEMBL8517588 0.81 NPC1 (0.45) CNR2EGFRERBB2PLA2G2ABLM
SCHEMBL11670713 0.81 MAPT (0.47) EGFRERBB2CNR1GAAMEN1
SCHEMBL7643003 0.81 PLA2G2A (0.46) CNR2PLA2G2ABLMNR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100159691-A1 PHOTOSENSITIVE RESIN COMPOSITION AND LAMINATE ASAHI KASEI EMD CORPORATION (JP) 2010-06-24 US disclosed