Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563932 | 0.90 | HTT (0.34) | TSHRMEN1KMT2APLAU | |
| SCHEMBL6565486 | 0.86 | PLAU (0.41) | TSHRSENP1MEN1KMT2APLAU | |
| SCHEMBL6563537 | 0.85 | PLAU (0.38) | TSHRKMT2APLAU | |
| SCHEMBL6563229 | 0.85 | PLAU (0.37) | TSHRKMT2APLAU | |
| SCHEMBL6565352 | 0.80 | PTPN11 (0.33) | — | |
| SCHEMBL6563507 | 0.79 | KCNK3 (0.31) | TSHRMEN1KMT2A | |
| SCHEMBL6565278 | 0.79 | PTPN11 (0.33) | — | |
| SCHEMBL6563093 | 0.79 | NQO2 (0.32) | L3MBTL1MEN1KMT2A | |
| SCHEMBL6565350 | 0.78 | HPGD (0.33) | MEN1KMT2A | |
| SCHEMBL6565305 | 0.78 | AAK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |