Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563752 | 0.90 | GAA (0.35) | KCNK3MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL6561673 | 0.87 | PRSS1 (0.35) | MEN1KMT2ATSHRALDH1A1GAA | |
| SCHEMBL6563605 | 0.85 | GAA (0.37) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL6565417 | 0.83 | PTPN11 (0.36) | KCNK3ALDH1A1GAAHPGDHSD11B1 | |
| SCHEMBL6561843 | 0.82 | GAA (0.31) | MEN1KMT2ATSHRGAAHSD11B1 | |
| SCHEMBL6561835 | 0.80 | PTPN11 (0.35) | KCNK3MEN1KMT2AALDH1A1GAA | |
| SCHEMBL6563002 | 0.79 | HRH3 (0.42) | ALDH1A1GAAHPGDHSD11B1HRH3 | |
| SCHEMBL6563591 | 0.79 | LRRK2 (0.39) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL6565367 | 0.79 | TSHR (0.31) | MEN1KMT2ATSHR | |
| SCHEMBL6563779 | 0.79 | KCNK3 (0.38) | KCNK3MEN1KMT2AGAAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |