Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561984 | 0.92 | MEN1 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL6564957 | 0.90 | F2 (0.38) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL6565372 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL6563364 | 0.88 | ITGB3 (0.36) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL6565424 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BPRSS1F2HSD11B1 | |
| SCHEMBL6565845 | 0.83 | F2 (0.36) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL6565512 | 0.83 | GAA (0.40) | PRSS1F2F10ALDH1A1HSD11B1 | |
| SCHEMBL6565376 | 0.82 | PRSS1 (0.35) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL6562329 | 0.81 | F2 (0.37) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL7806157 | 0.80 | MEN1 (0.38) | ITGB3ITGA2BF2F10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |