Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.35 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565424 | 0.92 | ITGB3 (0.42) | F2PRSS1HCRTR1HCRTR2ITGB3 | |
| SCHEMBL6563364 | 0.91 | ITGB3 (0.36) | F2PRSS1HCRTR1HCRTR2ITGB3 | |
| SCHEMBL6564957 | 0.87 | F2 (0.38) | F2PRSS1HCRTR1HCRTR2ITGB3 | |
| SCHEMBL6565845 | 0.87 | F2 (0.36) | F2PRSS1ITGB3ITGA2BF7 | |
| SCHEMBL6561984 | 0.86 | MEN1 (0.40) | F2PRSS1ITGB3ITGA2BF10 | |
| SCHEMBL6565512 | 0.83 | GAA (0.40) | F2PRSS1F10 | |
| SCHEMBL6565372 | 0.81 | ITGB3 (0.38) | F2PRSS1ITGB3ITGA2BF10 | |
| SCHEMBL6565523 | 0.81 | ITGB3 (0.38) | F2PRSS1HCRTR1HCRTR2ITGB3 | |
| SCHEMBL6565371 | 0.79 | KCNK3 (0.34) | HCRTR1HCRTR2ITGB3ITGA2B | |
| SCHEMBL6565851 | 0.79 | F2 (0.37) | F2PRSS1ITGB3ITGA2BF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |