SCHEMBL6565651

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL251842	0.82	MAOB (0.54)	ALDH1A1MAOBMETAP1ACHECYP19A1
	SCHEMBL29392039	0.82	MAOB (0.54)	ALDH1A1MAOBMETAP1ACHECYP19A1
	SCHEMBL5871789	0.79	MAOB (0.58)	ALDH1A1MAOBMAOAMETAP1ACHE
	SCHEMBL7272155	0.79	MAOB (0.52)	ALDH1A1MEN1APPMAPTSNCA
	SCHEMBL7272150	0.79	MAOB (0.52)	ALDH1A1MEN1APPMAPTSNCA
	Acetic Acid SCHEMBL6934641	0.78	MAOB (0.51)	ALDH1A1MAOBMETAP1ACHECYP19A1
	SCHEMBL19330670	0.78	METAP1 (0.51)	ALDH1A1MAPTMAOBMAOAMETAP1
	SCHEMBL19330671	0.78	METAP1 (0.51)	ALDH1A1MAPTMAOBMAOAMETAP1
	SCHEMBL31147657	0.78	MAPT (0.51)	ALDH1A1MEN1APPMAPTSNCA
	SCHEMBL356454	0.78	MAPT (0.51)	ALDH1A1MEN1APPMAPTSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.