Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358407 | 0.70 | EPHX2 (0.65) | EPHX2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4348756 | 0.70 | NPSR1 (0.55) | EPHX2NPSR1MAPTALDH1A1LMNA | |
| SCHEMBL4348906 | 0.68 | EPHX2 (0.73) | EPHX2NPSR1MAPTLMNAHTT | |
| SCHEMBL12932207 | 0.68 | MAPT (0.68) | EPHX2NPSR1MAPTMEN1KMT2A | |
| SCHEMBL25684474 | 0.67 | EPHX2 (0.84) | EPHX2LMNA | |
| SCHEMBL6568671 | 0.67 | POLB (0.40) | NPSR1MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3456422 | 0.66 | OGG1 (0.57) | NPSR1MAPTALDH1A1LMNAHTT | |
| SCHEMBL3069160 | 0.65 | EPHX2 (1.00) | EPHX2ALDH1A1LMNAHTT | |
| SCHEMBL4346744 | 0.65 | EPHX2 (1.00) | EPHX2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4346873 | 0.65 | EPHX2 (0.57) | EPHX2NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |