Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346754 | 0.71 | POLB (0.50) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL4346954 | 0.68 | KMT2A (0.40) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL4341979 | 0.68 | POLB (0.54) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL6565655 | 0.67 | EPHX2 (0.50) | HTTKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6566836 | 0.65 | EPHX1 (0.57) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL4341826 | 0.65 | HSPA5 (0.46) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL4358325 | 0.65 | POLB (0.60) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL4355807 | 0.65 | KMT2A (0.54) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL4354700 | 0.64 | CXCR1 (0.48) | POLBHTTKMT2AMEN1MAPT | |
| SCHEMBL6565514 | 0.64 | POLB (0.66) | POLBHTTKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |