Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14424478 | 0.82 | EPHX1 (0.80) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL7722626 | 0.81 | EPHX1 (0.97) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL17119069 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL5020899 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL4603476 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL813735 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL11671083 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL10599308 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL4138192 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 | |
| SCHEMBL422504 | 0.80 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |