Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | GHSR | Q92847 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599308 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL422504 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL4138192 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL4603476 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL813735 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL11671083 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL17119069 | 1.00 | EPHX1 (1.00) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL7722626 | 0.98 | EPHX1 (0.97) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| Dimethylamine SCHEMBL9100861 | 0.97 | EPHX1 (0.94) | EPHX1ALDH1A1HTTGHSRHDAC1 | |
| SCHEMBL4604785 | 0.93 | EPHX1 (0.87) | EPHX1ALDH1A1HTTGHSRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846710-B2 | Method of preferentially inducing the biosynthesis of interferon | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-30 | — | — | US | disclosed |
| US-8846710-B2 | Method of preferentially inducing the biosynthesis of interferon | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-30 | — | — | US | disclosed |
| US-8178677-B2 | Hydroxyalkyl substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178677-B2 | Hydroxyalkyl substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090029988-A1 | Hydroxyalkyl Substituted Imidazoquinolines | COLEY PHARMACEUTICAL GROP, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090029988-A1 | Hydroxyalkyl Substituted Imidazoquinolines | COLEY PHARMACEUTICAL GROP, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090030031-A1 | Method of Preferentially Inducing the Biosynthesis of Interferon | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090030031-A1 | Method of Preferentially Inducing the Biosynthesis of Interferon | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030031-A1 | Method of Preferentially Inducing the Biosynthesis of Interferon | IFNG, IFNAR1, EIF2AK2 | EPHX1 1109/4885ALDH1A1 1275/4885HTT 3984/4885 |
| US-20090029988-A1 | Hydroxyalkyl Substituted Imidazoquinolines | IFNG, IRF3, IFNAR1 | EPHX1 460/4885ALDH1A1 989/4885HTT 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.