Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GNA15 | P30679 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565086 | 0.89 | FFAR1 (0.41) | FFAR1PTGS2ALOX5GNA15MAOB | |
| SCHEMBL6566235 | 0.86 | VDR (0.43) | FFAR1PTGS2FFAR4 | |
| SCHEMBL6888111 | 0.80 | FFAR1 (0.36) | FFAR1PTGS2ALOX5FFAR4 | |
| SCHEMBL6564907 | 0.80 | FFAR1 (0.36) | FFAR1PTGS2ALOX5FFAR4 | |
| SCHEMBL6564911 | 0.80 | FFAR1 (0.40) | FFAR1PTGS2FFAR4 | |
| SCHEMBL6566293 | 0.76 | FFAR1 (0.51) | FFAR1FFAR4 | |
| SCHEMBL6565081 | 0.76 | VDR (0.43) | FFAR1ALOX5FFAR4 | |
| SCHEMBL7611585 | 0.74 | VDR (0.42) | FFAR1PTGS2ALOX5MEN1KMT2A | |
| SCHEMBL19961835 | 0.72 | MRGPRX4 (0.53) | FFAR1MAOBFFAR4 | |
| SCHEMBL6563103 | 0.71 | FFAR1 (0.45) | FFAR1ALOX5MEN1KMT2AGNA15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |