Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | GNA15 | P30679 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563099 | 0.80 | VDR (0.49) | FFAR1NR4A2F2MRGPRX4MAOB | |
| SCHEMBL2107020 | 0.77 | CYP4F2 (0.46) | FFAR1NR4A2APPNR4A1NR4A3 | |
| SCHEMBL6565086 | 0.74 | FFAR1 (0.41) | FFAR1GNA15NR4A2MAOBAPP | |
| SCHEMBL6562943 | 0.74 | FFAR1 (0.40) | FFAR1GNA15MRGPRX4MAOBALOX5 | |
| SCHEMBL7609494 | 0.74 | VDR (0.49) | FFAR1NR4A2F2MRGPRX4MAOB | |
| SCHEMBL27568058 | 0.74 | TSHR (0.46) | FFAR1NR4A2F2MRGPRX4MAOB | |
| SCHEMBL6155587 | 0.74 | CYSLTR2 (0.44) | FFAR1NR4A2APPALOX5NR4A1 | |
| SCHEMBL6886751 | 0.74 | BCHE (0.54) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6885228 | 0.73 | BCHE (0.53) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6566237 | 0.71 | FFAR1 (0.42) | FFAR1GNA15MAOBALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | claimed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |