Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566254 | 1.00 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6566251 | 1.00 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6565089 | 0.88 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6565092 | 0.88 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6565096 | 0.88 | CES2 (0.30) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6565121 | 0.82 | — | — | |
| SCHEMBL6565118 | 0.82 | — | — | |
| SCHEMBL6565115 | 0.82 | — | — | |
| SCHEMBL6564805 | 0.81 | ALDH1A1 (0.31) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6564814 | 0.81 | ALDH1A1 (0.31) | CES2CES1ALDH1A1LMNAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |