Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706072 | 0.87 | AGTR1 (0.57) | AGTR2AGTR1 | |
| SCHEMBL89 | 0.85 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL29486822 | 0.85 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL9468476 | 0.84 | AGTR1 (0.98) | AGTR2AGTR1 | |
| SCHEMBL9041377 | 0.83 | AGTR1 (0.74) | AGTR2AGTR1 | |
| SCHEMBL9042978 | 0.83 | PPARG (0.60) | AGTR2AGTR1 | |
| SCHEMBL9704742 | 0.83 | AGTR1 (0.55) | AGTR2AGTR1 | |
| SCHEMBL9042283 | 0.83 | AGTR1 (0.62) | AGTR2AGTR1 | |
| SCHEMBL462 | 0.83 | AGTR2 (0.80) | AGTR2AGTR1 | |
| SCHEMBL9704687 | 0.83 | AGTR2 (0.53) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014989-B1 | ENDOTHELIN ANTAGONIST AND A RENIN-ANGIOTENSIN SYSTEM INHIBITOR AS A COMBINED PREPARATION | ABBOTT GMBH & CO KG (DE) | 2004-01-14 | — | — | EP | disclosed |
| EP-0634175-B1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0634175-A1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-18 | — | — | EP | disclosed |