Bicarbonate

Bicarbonate

SCHEMBL6566447

C1CCC(OOC2CCCCC2)CC1.O=C(O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CYP2C19 P33261 1/20 0.38
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
NAAA Q02083 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
EPHX2 P34913 1/20 0.36
HTT P42858 1/20 0.35
FABP7 O15540 1/20 0.35
FABP5 Q01469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28775658 1.00 EPHX1 (0.43) EPHX1CES2CES1CA1CA2
Bicarbonate SCHEMBL366336 1.00 EPHX1 (0.43) EPHX1CES2CES1CA1CA2
SCHEMBL909903 0.87 EPHX1 (0.39) EPHX1CES2CES1CA1CA2
SCHEMBL36848 0.84 CA1 (0.41) EPHX1CES2CES1CA1CA2
SCHEMBL28573115 0.84 CA1 (0.41) EPHX1CES2CES1CA1CA2
SCHEMBL11679637 0.84 CA1 (0.41) EPHX1CES2CES1CA1CA2
SCHEMBL11638037 0.84 CA1 (0.41) EPHX1CES2CES1CA1CA2
SCHEMBL6507671 0.81 EPHX1 (0.39) EPHX1CES2CES1CA1CA2
SCHEMBL7015517 0.81 EPHX1 (0.43) EPHX1CES2CES1CA1CA2
SCHEMBL15157468 0.81 CA1 (0.39) EPHX1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444809-A1 ADHESIVES COMPRISING CYCLIC IMIDE ADDITION-FRAGMENTATION AND ADHESION AGENTS 3M Innovative Properties Company (US) 2024-10-16 EP disclosed
EP-4377367-A1 COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, AN ALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLE AND METHOD 3M Innovative Properties Company (US) 2024-06-05 EP disclosed
EP-4263640-A1 COMPOSITION INCLUDING AN ACRYLIC MONOMER WITH A CARBOXYLIC ACID GROUP, AN ACRYLIC MONOMER WITH A HYDROXYL GROUP, AN ALKYL (METH)ACRYLATE MONOMER AND CROSSLINKER, AND RELATED ARTICLES AND METHODS 3M Innovative Properties Company (US) 2023-10-25 EP disclosed
EP-4244268-A1 FREE-RADICALLY POLYMERIZABLE CROSSLINKER, CURABLE COMPOSITION, AND ADHESIVE THEREFROM 3M Innovative Properties Company (US) 2023-09-20 EP disclosed
EP-4244267-A1 FREE-RADICALLY POLYMERIZABLE CROSSLINKER, CURABLE COMPOSITION, AND ADHESIVE THEREFROM 3M Innovative Properties Company (US) 2023-09-20 EP disclosed
WO-2023166342-A1 POLYMERIZABLE COMPOSITIONS INCLUDING A POLYMERIZABLE COMPONENT AND A REDOX INITIATION SYSTEM CONTAINING A PHOTOLABILE REDUCING AGENT, AND A PHOTOLABILE REDUCING AGENT 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-09-07 WO disclosed
EP-4196510-A1 (METH)ACRYLATE STRUCTURAL ADHESIVES AND METHODS 3M Innovative Properties Company (US) 2023-06-21 EP disclosed
WO-2023105327-A1 ADHESIVES COMPRISING CYCLIC IMIDE ADDITION-FRAGMENTATION AND ADHESION AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-06-15 WO disclosed
WO-2023007401-A1 COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, AN ALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLE AND METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-02 WO disclosed
WO-2022130340-A1 COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, A CYCLOALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-23 WO disclosed
EP-0699312-B1 METHOD FOR MAKING COLORED CONTACT LENSES AND COLOR COATING COMPOSITION BENSKY FREDDIE (FI) 2000-03-08 EP disclosed
WO-1999031155-A1 METHOD FOR GRAFTING LIGNIN, POLYMERIZATES PRODUCED ACCORDING TO THE METHOD AND THE UTILIZATION THEREOF STOCKHAUSEN GMBH & CO. KG (DE) 1999-06-24 WO disclosed
EP-0824553-B1 WATER-SOLUBLE COPOLYMERS, PROCESS FOR PRODUCING THE SAME AND THEIR USE STOCKHAUSEN CHEM FAB GMBH (DE) 1999-02-17 EP disclosed
EP-0824553-A1 WATER-SOLUBLE COPOLYMERS, PROCESS FOR PRODUCING THE SAME AND THEIR USE STOCKHAUSEN GmbH & CO. KG (DE) 1998-02-25 EP disclosed
WO-1996035728-A1 WATER-SOLUBLE COPOLYMERS, PROCESS FOR PRODUCING THE SAME AND THEIR USE STOCKHAUSEN GMBH & CO. KG (DE) 1996-11-14 WO disclosed
EP-0699312-A1 METHOD FOR MAKING COLORED CONTACT LENSES AND COLOR COATING COMPOSITION BENSKY, Freddie (FI) 1996-03-06 EP disclosed
WO-1994027178-A1 METHOD FOR MAKING COLORED CONTACT LENSES AND COLOR COATING COMPOSITION BENSKY FREDDIE (FI) 1994-11-24 WO disclosed
EP-0031521-B1 METHOD OF MAKING ALTERNATION-PROOF DOCUMENTS Agfa-Gevaert AG (DE) 1984-08-22 EP disclosed
EP-0031521-A2 Method of making alternation-proof documents Agfa-Gevaert AG (DE) 1981-07-08 EP disclosed
US-4259229-A Process for producing colored polymer NIKITIN JURY E 1981-03-31 US disclosed