Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22733772 | 0.82 | EPHX1 (0.40) | EPHX1CES2CES1CA1CA2 | |
| Bicarbonate SCHEMBL28775658 | 0.81 | EPHX1 (0.43) | EPHX1CES2CES1CA1CA2 | |
| Bicarbonate SCHEMBL6566447 | 0.81 | EPHX1 (0.43) | EPHX1CES2CES1CA1CA2 | |
| Bicarbonate SCHEMBL366336 | 0.81 | EPHX1 (0.43) | EPHX1CES2CES1CA1CA2 | |
| SCHEMBL7106072 | 0.80 | EPHX1 (0.39) | EPHX1CES2CES1CA1CA2 | |
| SCHEMBL6507671 | 0.80 | EPHX1 (0.39) | EPHX1CES2CES1CA1CA2 | |
| SCHEMBL29525024 | 0.79 | EPHX1 (0.37) | EPHX1CES2CES1CA1CA2 | |
| SCHEMBL21381 | 0.78 | EPHX1 (0.39) | EPHX1CES2CES1CA1CA2 | |
| SCHEMBL6326356 | 0.78 | EPHX1 (0.38) | EPHX1CES2CES1CA1CA2 | |
| SCHEMBL11504811 | 0.76 | EPHX1 (0.45) | EPHX1CA1CA2CYP2C19NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520423-B1 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-14 | — | — | EP | claimed |
| EP-0520423-B1 | Heterocyclic compounds, their production and use as angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-14 | — | — | EP | disclosed |