Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661033 | 0.83 | KIF11 (0.44) | MAPK1KIF11KCNN4MEN1KMT2A | |
| SCHEMBL7877164 | 0.82 | MAPK1 (0.44) | MAPK1KIF11KCNN4MEN1KMT2A | |
| SCHEMBL28682767 | 0.80 | MAPK1 (0.67) | MAPK1KIF11KCNN4TAAR1ALDH1A1 | |
| SCHEMBL7876812 | 0.80 | MAPK1 (0.48) | MAPK1KCNN4TAAR1ALDH1A1ALOX15 | |
| SCHEMBL11106032 | 0.79 | LTA4H (0.44) | MAPK1KIF11KCNN4ALDH1A1LTA4H | |
| SCHEMBL297786 | 0.77 | MAPK1 (0.52) | MAPK1KIF11KCNN4MEN1KMT2A | |
| SCHEMBL28439913 | 0.77 | KIF11 (0.42) | MAPK1KIF11KCNN4MEN1KMT2A | |
| SCHEMBL2350021 | 0.76 | KIF11 (0.56) | MAPK1KIF11KCNN4TAAR1ALDH1A1 | |
| SCHEMBL21679652 | 0.74 | KIF11 (0.36) | MAPK1KIF11KCNN4TAAR1ALDH1A1 | |
| SCHEMBL28292741 | 0.74 | MAPK1 (0.63) | MAPK1KIF11KCNN4TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447408-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and therapeutics produced therewith | Rohm and Haas Company (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20040158037-A1 | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith | BOHLING JAMES CHARLES (US) | 2004-08-12 | — | — | US | disclosed |