Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6566204 | 0.99 | CNR1 (0.56) | CNR1CA1CA2CA9CA12 | |
| SCHEMBL6566904 | 0.82 | ALDH1A1 (0.57) | CNR1ALDH1A1F10HTTSMN1; SMN2 | |
| SCHEMBL6387305 | 0.79 | LSS (0.49) | CNR1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL6393419 | 0.78 | F10 (0.73) | CNR1CA1CA2CA9CA12 | |
| SCHEMBL4485606 | 0.76 | NSD2 (0.51) | CNR1CA1CA2CA9NSD2 | |
| SCHEMBL4470111 | 0.72 | NSD2 (0.71) | ALDH1A1NSD2HTTNPSR1MAPT | |
| SCHEMBL9738489 | 0.72 | CA12 (0.66) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL11122558 | 0.72 | HDAC4 (0.57) | PRSS1PRSS2PRSS3NSD2 | |
| SCHEMBL1816382 | 0.71 | CA12 (0.50) | CA9CA12ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7111715 | 0.71 | CA12 (0.67) | CA9CA12ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |