Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568071 | 0.82 | F10 (0.64) | ALDH1A1SMN1; SMN2HTTPOLBTP53 | |
| SCHEMBL6566898 | 0.82 | CNR1 (0.57) | ALDH1A1SMN1; SMN2CNR1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL6566204 | 0.81 | CNR1 (0.56) | ALDH1A1SMN1; SMN2CNR1HTTMEN1 | |
| SCHEMBL6390564 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CNR1HTTPOLB | |
| SCHEMBL15473866 | 0.78 | POLB (0.62) | ALDH1A1SMN1; SMN2HTTPOLB | |
| SCHEMBL10461810 | 0.76 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HTTF10 | |
| SCHEMBL3564486 | 0.76 | L3MBTL1 (0.64) | ALDH1A1SMN1; SMN2POLBTP53 | |
| SCHEMBL15467870 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7486079 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4617734 | 0.74 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2HTTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |