Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903284 | 0.86 | TSHR (0.58) | TSHRHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL9570919 | 0.85 | ALDH1A1 (0.54) | TSHRHTTBCAT2HPGDKDM4E | |
| SCHEMBL9844764 | 0.83 | KDM4E (0.49) | TSHRHTTBCAT2HPGDKDM4E | |
| SCHEMBL6566957 | 0.82 | TSHR (0.55) | TSHRHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL9329299 | 0.82 | TSHR (0.46) | TSHRHTTBCAT2HPGDKDM4E | |
| SCHEMBL6075765 | 0.82 | TSHR (0.46) | TSHRHTTBCAT2HPGDKDM4E | |
| SCHEMBL7255678 | 0.82 | HTT (0.62) | TSHRHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL3973663 | 0.82 | KMT2A (0.45) | TSHRHTTBCAT2HPGDKDM4E | |
| SCHEMBL15796793 | 0.82 | KMT2A (0.67) | HTTKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL4138337 | 0.81 | CTSD (0.55) | TSHRHTTBCAT2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7186538-A | — | — | None | — | — | JP | disclosed |
| US-20250340507-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-11-06 | — | — | US | disclosed |
| CN-111527075-A | Xanthene compound, photosensitive resin composition containing the same, photosensitive material, color filter, and display device | 株式会社LG化学 | 2020-08-11 | — | — | CN | disclosed |
| US-20170283368-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2017-10-05 | — | — | US | disclosed |
| US-9522872-B2 | Methods for synthesizing substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| WO-2014005125-A2 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| CN-103460086-A | Colored composition for color filters, and color filters | TOYO INK SC HOLDINGS CO LTD | 2013-12-18 | — | — | CN | disclosed |
| EP-2176216-B1 | METHODS FOR SYNTHESIZING 9-SUBSTITUTED MINOCYCLINE | PARATEK PHARM INNC (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2192111-A2 | Methods for synthesizing substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-2176216-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |
| US-4791204-A | FOR COLORING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |
| US-4678611-A | Novel dyestuff intermediates and use thereof for the manufacture of novel azo dyes | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0073826-A1 | RAPID SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORUS OXYCHLORIDE ACTIVATION | BIORESEARCH INC. (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4360460-A | Novel azo dyes having a 4-sulfo-5-aminomethyl naphthalene coupling moiety | CIBA-GEIGY AG (CH) | 1982-11-23 | — | — | US | disclosed |
| WO-1982003079-A1 | RAPID SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORUS OXYCHLORIDE ACTIVATION | BIORESEARCH INC (US) | 1982-09-16 | — | — | WO | disclosed |
| US-4288363-A | Novel azo dyes having 2-amino-5-aminomethyl-7-sulfo naphthalene coupling moiety | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4222777-A | RADIOGRAPHY, PROCESSING FREE OF SILVER BLEACHING STEP | FUJI PHOTO FILM CO., LTD. (JP) | 1980-09-16 | — | — | US | disclosed |
| US-4154615-A | GRAFT POLYMERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-05-15 | — | — | US | disclosed |
| US-4092414-A | 3,4-Dihydrospiro-2H-1,3-benzoxazines and their use in treating edema, abnormal electrolyte retention, and inflammation | MERCK & CO., INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4070464-A | DISPIROBENZOXAZINES | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250340507-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | TET3, TET1, DHFR | TSHR 2369/4885HTT 571/4885BCAT2 305/4885 |
| US-20170283368-A1 | METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS | TET3, TET1, DHFR | TSHR 2369/4885HTT 571/4885BCAT2 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.