SCHEMBL6567013

SCHEMBL6567013

c1c[nH]c(Sc2ccc[nH]2)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
INCENP Q9NQS7 1/20 0.35
FKBP5 Q13451 1/20 0.33
MCL1 Q07820 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1861866 0.82 TUBB4A (0.39) FKBP5MCL1KDM4EMAPT
SCHEMBL8691932 0.81 DAO (0.35) DAOHDAC8HDAC6AURKAAURKB
SCHEMBL11820016 0.77
SCHEMBL5188834 0.77
SCHEMBL30640511 0.77
SCHEMBL6209082 0.77
SCHEMBL1862371 0.77
SCHEMBL6323857 0.77
SCHEMBL3299719 0.77
SCHEMBL3489515 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113583985-B Mono-oxygenase mutant capable of being secreted efficiently in pichia pastoris and application 华东理工大学 2023-08-01 CN claimed
CN-109467527-A Tartaric acid sulfur ester and its preparation method and application 江苏奥赛康药业股份有限公司 2019-03-15 CN claimed
CN-108117547-A Fluorescence probe based on quinokysalines aryl thioethers class and its preparation method and application 上海交通大学 2018-06-05 CN claimed
US-4699645-A Azolyl-thioether derivatives as fungicides and plant growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1987-10-13 US claimed
US-4559077-A TRIAZOLE OR IMIDAZOLE BAYER AKTIENGESELLSCHAFT (DE) 1985-12-17 US claimed
EP-0086901-B1 AZOLYL-THIOETHER DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND PLANT GROWTH REGULATORS BAYER AG (DE) 1985-12-04 EP claimed
JP-2085267-A None JP disclosed
CN-114836395-B Thioether monooxygenase mutant and application thereof in preparation of chiral azole drugs 华东理工大学 2024-04-26 CN disclosed
CN-112725297-B Thioether monooxygenase and application thereof in preparation of chiral azole drugs 华东理工大学 2023-12-29 CN disclosed
CN-117016550-A Sterilization composition and application thereof 沈阳中化农药化工研发有限公司 2023-11-10 CN disclosed
CN-117016551-A Sterilization composition and application thereof 沈阳中化农药化工研发有限公司 2023-11-10 CN disclosed
CN-116711727-A Sterilization composition and application thereof 沈阳中化农药化工研发有限公司 2023-09-08 CN disclosed
CN-113583985-B Mono-oxygenase mutant capable of being secreted efficiently in pichia pastoris and application 华东理工大学 2023-08-01 CN disclosed
EP-0143424-A2 Heat-developable light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1985-06-05 EP disclosed
EP-0086901-A1 Azolyl-thioether derivatives, process for their preparation and their use as fungicides and plant growth regulators BAYER AG (DE) 1983-08-31 EP disclosed
US-4291120-A VINYLPHENOL POLYMER AS ADHESION IMPROVER FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed
US-4281060-A STABLE PHOTOGRAPHIC FILMS HAVING A COATING CONTAINING A POLYISOCYANATE OR A POLYISOCYANATE CONTAINING CARBAMATE GROUPS; WEAR RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1981-07-28 US disclosed
US-4237213-A THERMOGRAPHY; PHOTOSENSITIVE MATERIAL CONTAINING ORGANIC SILVER SALT, HALIDE, AND BINDER CANON KABUSHIKI KAISHA (JP) 1980-12-02 US disclosed
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US disclosed
US-3839041-A STABILIZER PRECURSORS IN PHOTOTHERMOGRAPHIC ELEMENTS AND COMPOSITIONS EASTMAN KODAK CO 1974-10-01 US disclosed