⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21271950 | 0.82 | MMP1 (0.40) | — | |
| Iminobis(Methylphosphonic Acid) SCHEMBL357369 | 0.81 | KDM4E (0.44) | — | |
| SCHEMBL4422829 | 0.78 | — | — | |
| Diethylamine SCHEMBL29187214 | 0.78 | TP53 (0.57) | — | |
| Diethylamine SCHEMBL320756 | 0.78 | TP53 (0.57) | — | |
| Diethylamine SCHEMBL9484949 | 0.78 | TP53 (0.57) | — | |
| Diethylamine SCHEMBL1203507 | 0.78 | TP53 (0.57) | — | |
| Medronic Acid SCHEMBL10395759 | 0.77 | MMP2 (0.59) | — | |
| Hydrochloric Acid SCHEMBL16225606 | 0.76 | ANPEP (0.52) | — | |
| Diethylamine SCHEMBL29262325 | 0.75 | TP53 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001507695-A | — | — | 2001-06-12 | — | — | JP | claimed |
| EP-0948507-A1 | HYDROGENATION OF CYANOPHOSPHONATE DERIVATIVES | MONSANTO COMPANY (US) | 1999-10-13 | — | — | EP | claimed |
| US-5905163-A | REDUCTION OF CYANO GROUP BY CATALYTIC HYDROGENATION | MONSANTO COMPANY (US) | 1999-05-18 | — | — | US | claimed |
| WO-1998029423-A1 | HYDROGENATION OF CYANOPHOSPHONATE DERIVATIVES | MONSANTO COMPANY (US) | 1998-07-09 | — | — | WO | claimed |
| US-9150419-B2 | Polycrystalline articles for reagent delivery | US SYNTHETIC CORPORATION (US) | 2015-10-06 | — | — | US | disclosed |
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20040236144-A1 | Method for producing $g(a)-aminophosphonic acids | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1401847-A1 | METHOD FOR PRODUCING $G(A)-AMINOPHOSPHONIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003000702-A1 | METHOD FOR PRODUCING $G(A)-AMINOPHOSPHONIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
| US-5099056-A | PROCESS FOR THE PRODUCTION OF N-SUBSTITUTED-AMINOMETHYLPHOSPHONIC ACID DIALKYLESTERS AND OF THE CORRESPONDING ACIDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-03-24 | — | — | US | disclosed |
| EP-0385014-A1 | Process for preparation of substituted aminomethylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| EP-0385010-A1 | N-alkyl-N-(Aminophenylsulfonyl)-aminoalkylphosphonic acids and salts | CROMPTON & KNOWLES CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4851158-A | N-alkyl-N-(aminophenylsulfonyl)-aminoalkylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| US-4830788-A | Process for preparation of substituted-aminomethylphosphonic acids | CROMPTON & KNOWLES CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4804500-A | Amine dealkylation process | MONSANTO COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0199702-B1 | AMINE DEALKYLATION PROCESS | Monsanto Company (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0199702-A1 | Amine dealkylation process | Monsanto Company (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0186648-A1 | Process for the preparation of glyphosate and glyphosate derivatives | Monsanto Company (US) | 1986-07-02 | — | — | EP | disclosed |