Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9041880 | 0.96 | AGTR1 (0.76) | AGTR1AGTR2 | |
| SCHEMBL9042546 | 0.93 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9042684 | 0.91 | AGTR1 (0.74) | AGTR1AGTR2 | |
| Trifluoroacetic Acid SCHEMBL9044417 | 0.91 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9043339 | 0.91 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL9040872 | 0.90 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9041554 | 0.90 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9040646 | 0.90 | AGTR2 (0.73) | AGTR1AGTR2 | |
| SCHEMBL6567316 | 0.90 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL9044581 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724387-B1 | ANGIOTENSION II RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CHRONIC ANTI-INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | claimed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | claimed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | claimed |
| EP-1014989-B1 | ENDOTHELIN ANTAGONIST AND A RENIN-ANGIOTENSIN SYSTEM INHIBITOR AS A COMBINED PREPARATION | ABBOTT GMBH & CO KG (DE) | 2004-01-14 | — | — | EP | disclosed |
| EP-0634175-B1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0634175-A1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-18 | — | — | EP | disclosed |