Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336186 | 1.00 | ALDH1A1 (0.37) | ALDH1A1USP2LMNACYP1A2TSHR | |
| SCHEMBL27360095 | 0.78 | ALDH1A1 (0.35) | ALDH1A1USP2LMNACYP1A2TSHR | |
| Aspartic Acid SCHEMBL6706587 | 0.76 | GRIK1 (0.42) | ALDH1A1USP2LMNACYP1A2TSHR | |
| SCHEMBL7646569 | 0.74 | CYP2C19 (0.38) | ALDH1A1USP2LMNACYP1A2TSHR | |
| SCHEMBL17933639 | 0.69 | TSHR (0.34) | ALDH1A1USP2LMNACYP1A2TSHR | |
| SCHEMBL28478525 | 0.69 | TSHR (0.34) | ALDH1A1USP2LMNACYP1A2TSHR | |
| Aspartic Acid SCHEMBL376347 | 0.68 | SLC22A6 (0.39) | LMNACYP1A2SMN1; SMN2DPP4GRIK1 | |
| Aspartic Acid SCHEMBL2728797 | 0.68 | SLC22A6 (0.39) | LMNACYP1A2SMN1; SMN2DPP4GRIK1 | |
| Propionic Acid SCHEMBL8331569 | 0.67 | FFAR3 (0.46) | ALDH1A1USP2LMNACYP1A2TSHR | |
| SCHEMBL20104759 | 0.67 | MME (0.39) | ALDH1A1USP2LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438968-A1 | Topical compositions containing at least one polypeptide hydrolase with an amidasic activity and /or compounds capable of modulating this activity | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |