Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27360095 | 0.75 | ALDH1A1 (0.35) | CYP2C19MMEALDH1A1USP2LMNA | |
| SCHEMBL6567364 | 0.74 | ALDH1A1 (0.37) | CYP2C19MMEALDH1A1USP2LMNA | |
| SCHEMBL3336186 | 0.74 | ALDH1A1 (0.37) | CYP2C19MMEALDH1A1USP2LMNA | |
| SCHEMBL6442112 | 0.70 | — | — | |
| SCHEMBL1072994 | 0.70 | — | — | |
| SCHEMBL333107 | 0.70 | — | — | |
| SCHEMBL27382096 | 0.69 | MME (0.31) | MME | |
| SCHEMBL8336948 | 0.68 | ALDH1A1 (0.34) | ALDH1A1USP2LMNACYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL28036339 | 0.68 | SLC22A6 (0.41) | LMNACYP1A2BLMSMN1; SMN2GRM1 | |
| SCHEMBL11700802 | 0.67 | GRIK1 (0.33) | CYP2C19MMEALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084138-B1 | METHOD FOR PREPARING ASPARTYL CYCLOHEXYLALANINAMIDE | AVENTIS PHARMA SA (FR) | 2002-01-30 | — | — | EP | claimed |
| EP-1084138-B1 | METHOD FOR PREPARING ASPARTYL CYCLOHEXYLALANINAMIDE | AVENTIS PHARMA SA (FR) | 2002-01-30 | — | — | EP | disclosed |
| EP-1084138-A1 | METHOD FOR PREPARING ASPARTYL CYCLOHEXYLALANINAMIDE | Aventis Pharma S.A. (FR) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999064443-A1 | METHOD FOR PREPARING ASPARTYL CYCLOHEXYLALANINAMIDE | AVENTIS PHARMA S.A. (FR) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999064443-A1 | METHOD FOR PREPARING ASPARTYL CYCLOHEXYLALANINAMIDE | AVENTIS PHARMA S.A. (FR) | 1999-12-16 | — | — | WO | disclosed |