Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12416800 | 0.88 | S100B (0.58) | S100BCA2CA1KMT2AMAPT | |
| SCHEMBL12306095 | 0.85 | NPC1 (0.53) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL12416648 | 0.85 | NPC1 (0.53) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13038181 | 0.85 | CA2 (0.76) | S100BCA2CA1KMT2AMAPT | |
| SCHEMBL11438347 | 0.85 | CA2 (0.76) | S100BCA2CA1KMT2AMAPT | |
| SCHEMBL11438344 | 0.85 | CA2 (0.76) | S100BCA2CA1KMT2AMAPT | |
| SCHEMBL27824110 | 0.83 | SMN1; SMN2 (0.64) | CA2CA1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10611991 | 0.82 | MAPT (0.53) | S100BCA2CA1KMT2AMAPT | |
| SCHEMBL13256587 | 0.81 | SMN1; SMN2 (0.62) | CA2CA1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8756800 | 0.81 | CA2 (0.62) | S100BCA2CA1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173411-B1 | POLYALDIMINES OF OLIGOMERIC AMINOBENZOIC ACID DERIVATIVES, AND THEIR USE FOR PREPARATION OF MOISTURE-CURABLE, STORAGE-STABLE, ONE-PART POLYREAS | SAWYER KENNETH I (US) | 2004-04-07 | — | — | EP | disclosed |
| US-6552155-B1 | Blocked poly(1,4-butanediol)bis(4-aminobenzoate); formulations with polyisocyanates; rapid curing when exposed to water or air humidity; anticorrosive coating, antifouling paint, caulking, sealing, waterproofing | Sawyer, Kenneth I. | 2003-04-22 | — | — | US | disclosed |