Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947815 | 0.83 | HPGD (0.62) | L3MBTL1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL16150319 | 0.80 | CYP3A4 (0.66) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL22693561 | 0.79 | S1PR2 (0.56) | L3MBTL1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL6226646 | 0.79 | KDM4E (0.45) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL8415139 | 0.77 | MEN1 (0.62) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL23518545 | 0.77 | L3MBTL1 (0.57) | L3MBTL1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL9402610 | 0.77 | GAA (0.59) | L3MBTL1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL13139888 | 0.77 | HPGD (0.56) | L3MBTL1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL27664708 | 0.76 | ADORA2A (0.60) | L3MBTL1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL23518443 | 0.75 | RAB9A (0.76) | L3MBTL1HPGDMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |