Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.65 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3321984 | 0.84 | P2RX7 (0.72) | P2RX7MEN1KMT2AGPR55USP2 | |
| SCHEMBL6941695 | 0.83 | P2RX7 (0.65) | P2RX7MEN1KMT2AGPR55USP2 | |
| SCHEMBL6939890 | 0.81 | P2RX7 (0.70) | P2RX7MEN1KMT2AGPR55USP2 | |
| SCHEMBL6940565 | 0.78 | P2RX7 (1.00) | P2RX7MEN1KMT2AUSP2 | |
| SCHEMBL6941699 | 0.78 | P2RX7 (0.70) | P2RX7MEN1KMT2AGPR55USP2 | |
| SCHEMBL12932448 | 0.77 | P2RX7 (0.75) | P2RX7MEN1KMT2AGPR55USP2 | |
| SCHEMBL4348906 | 0.77 | EPHX2 (0.73) | P2RX7P2RX5P2RX4P2RX2MEN1 | |
| SCHEMBL6941160 | 0.75 | P2RX7 (0.67) | P2RX7KMT2AGPR55EPHX2POLB | |
| SCHEMBL11884308 | 0.75 | P2RX7 (1.00) | P2RX7MEN1KMT2AGPR55USP2 | |
| SCHEMBL6941644 | 0.74 | P2RX7 (1.00) | P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |