Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567684 | 0.80 | MMP8 (0.45) | SCN5ASCN9AKMT2AALDH1A1MEN1 | |
| SCHEMBL4811289 | 0.74 | SCN9A (0.38) | SCN5ASCN9AALDH1A1MAPTCYP3A4 | |
| SCHEMBL21233754 | 0.72 | KMT2A (0.61) | SCN9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL21233885 | 0.72 | KMT2A (0.61) | SCN9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12251345 | 0.70 | KMT2A (0.63) | SCN9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL10405578 | 0.69 | KMT2A (0.65) | SCN9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL9062437 | 0.69 | KMT2A (0.65) | SCN9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL5023233 | 0.68 | MMP8 (0.60) | ALDH1A1MME | |
| SCHEMBL14963194 | 0.68 | KMT2A (0.59) | SCN9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8310339 | 0.68 | ERCC1 (0.56) | ALDH1A1CYP3A4TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404664-A1 | AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003006453-A1 | AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |