Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MASP2 | O00187 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567682 | 0.80 | SCN5A (0.43) | ALDH1A1KMT2ASCN5ASCN9AMME | |
| SCHEMBL21233885 | 0.73 | KMT2A (0.61) | MMP8ALDH1A1KMT2ASCN9AMME | |
| SCHEMBL21233754 | 0.73 | KMT2A (0.61) | MMP8ALDH1A1KMT2ASCN9AMME | |
| SCHEMBL13333829 | 0.73 | MASP2 (0.48) | ALDH1A1KMT2AMASP2F2CYP3A4 | |
| SCHEMBL3356614 | 0.73 | MASP2 (0.48) | ALDH1A1KMT2AMASP2F2CYP3A4 | |
| SCHEMBL14577806 | 0.73 | MASP2 (0.48) | ALDH1A1KMT2AMASP2F2CYP3A4 | |
| SCHEMBL14614227 | 0.72 | KMT2A (0.54) | MMP8ALDH1A1SMN1; SMN2KMT2AMME | |
| SCHEMBL12251345 | 0.71 | KMT2A (0.63) | MMP8ALDH1A1SMN1; SMN2KMT2ASCN9A | |
| SCHEMBL7615257 | 0.71 | BACE1 (0.54) | BACE1BACE2 | |
| SCHEMBL5389600 | 0.71 | BACE1 (0.54) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404664-A1 | AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003006453-A1 | AMINEDIOLS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |