Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413361 | 0.87 | THRB (0.56) | KMT2AMAPTSMN1; SMN2MEN1TDP1 | |
| SCHEMBL3841280 | 0.87 | THRB (0.56) | KMT2AMAPTSMN1; SMN2MEN1TDP1 | |
| SCHEMBL725404 | 0.84 | KMT2A (0.76) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL4908371 | 0.84 | KMT2A (0.61) | KMT2AMAPTMEN1TDP1L3MBTL1 | |
| Bromide SCHEMBL29588519 | 0.82 | KMT2A (0.73) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| Hydrochloric Acid SCHEMBL16050041 | 0.82 | KMT2A (0.73) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL14173222 | 0.81 | THRB (0.51) | KMT2AMAPTSMN1; SMN2MEN1TDP1 | |
| SCHEMBL5517406 | 0.81 | THRB (0.51) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL5530470 | 0.81 | TDP1 (0.51) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL27891498 | 0.81 | SLC6A3 (0.63) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |