Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24425884 | 1.00 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL19351731 | 1.00 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL284812 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL11337797 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL14972401 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL11909573 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL14244897 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL11326465 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL20547697 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR | |
| SCHEMBL11322829 | 0.96 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTABCC4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| EP-2711351-A1 | Low catalyst loading in metathesis reactions | Evonik Industries AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-8648003-B2 | Catalysts for ring-closing metathesis | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-02-11 | — | — | US | disclosed |
| US-8648003-B2 | Catalysts for ring-closing metathesis | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-02-11 | — | — | US | disclosed |
| US-8501656-B2 | — | — | 2013-08-06 | — | — | US | disclosed |
| US-8501656-B2 | — | — | 2013-08-06 | — | — | US | disclosed |
| US-20130131353-A1 | CATALYSTS FOR RING-CLOSING METATHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-05-23 | — | — | US | disclosed |
| US-20130131353-A1 | CATALYSTS FOR RING-CLOSING METATHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-05-23 | — | — | US | disclosed |
| US-20090170692-A1 | CATALYSTS FOR RING-CLOSING METATHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2009-07-02 | — | — | US | disclosed |
| US-20090170692-A1 | CATALYSTS FOR RING-CLOSING METATHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2009-07-02 | — | — | US | disclosed |
| WO-2007117221-A1 | CATALYSTS FOR RING CLOSING METATHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2007-10-18 | — | — | WO | disclosed |
| EP-0927577-B1 | Ruthenium metathesis catalyst and method for olefin metathesis using the same | TAKASAGO PERFUMERY CO LTD (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-6313365-B1 | Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| US-6175047-B1 | A CATALYST MIXTURE INCLUDING A RUTHENIUM COMPOUND, A DIHALOGENO COMPOUND, A TERMINAL ALKYNE; AS A CATALYST FOR A CARBON-CARBON BOND FORMATION REACTION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0927577-A1 | Ruthenium metathesis catalyst and method for producing olefin reaction product by metathesis reaction using the same | Takasago International Corporation (JP) | 1999-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | APEX1, PMS2, MAX | ALDH1A1 2091/4885LMNA 2185/4885MAPT 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.