Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959163 | 1.00 | LTA4H (0.45) | LTA4HSMN1; SMN2SLC6A1SLC6A9RAB9A | |
| SCHEMBL4959171 | 1.00 | LTA4H (0.45) | LTA4HSMN1; SMN2SLC6A1SLC6A9RAB9A | |
| SCHEMBL4877586 | 0.95 | SMN1; SMN2 (0.50) | LTA4HSMN1; SMN2SLC6A1SLC6A9GBA1 | |
| SCHEMBL22585402 | 0.91 | LTA4H (0.42) | LTA4HSMN1; SMN2SLC6A1SLC6A9RAB9A | |
| SCHEMBL16418017 | 0.90 | SMN1; SMN2 (0.43) | LTA4HSMN1; SMN2SLC6A1SLC6A9RAB9A | |
| SCHEMBL23920574 | 0.87 | SMN1; SMN2 (0.41) | LTA4HSMN1; SMN2SLC6A1SLC6A9RAB9A | |
| SCHEMBL30639643 | 0.85 | LTA4H (0.41) | LTA4HSMN1; SMN2GBA1 | |
| SCHEMBL16418012 | 0.85 | LTA4H (0.56) | LTA4HGBA1 | |
| SCHEMBL23715749 | 0.85 | LTA4H (0.56) | LTA4HGBA1 | |
| SCHEMBL13555216 | 0.82 | SMN1; SMN2 (0.47) | LTA4HSMN1; SMN2SLC6A1RAB9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |