Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155228 | 0.90 | SCN3A (0.39) | LTA4HSMN1; SMN2SPHK1SCN3APOLB | |
| SCHEMBL4959171 | 0.85 | LTA4H (0.45) | LTA4HGBA1SMN1; SMN2 | |
| SCHEMBL4959163 | 0.85 | LTA4H (0.45) | LTA4HGBA1SMN1; SMN2 | |
| SCHEMBL6568062 | 0.85 | LTA4H (0.45) | LTA4HGBA1SMN1; SMN2 | |
| SCHEMBL23715749 | 0.83 | LTA4H (0.56) | LTA4HGBA1ALDH1A1MAPTPOLB | |
| SCHEMBL16418012 | 0.83 | LTA4H (0.56) | LTA4HGBA1ALDH1A1MAPTPOLB | |
| SCHEMBL4555126 | 0.83 | SPHK1 (0.40) | SMN1; SMN2SPHK1SCN3APOLBMAOA | |
| SCHEMBL18555352 | 0.83 | SPHK1 (0.40) | SMN1; SMN2SPHK1SCN3APOLBMAOA | |
| SCHEMBL3289140 | 0.81 | LMNA (0.47) | SMN1; SMN2SPHK1ALDH1A1SCN3APOLB | |
| SCHEMBL3289131 | 0.81 | LMNA (0.47) | SMN1; SMN2SPHK1ALDH1A1SCN3APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504720-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196659-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2023-10-12 | — | — | WO | disclosed |