Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803064 | 0.91 | HPGD (0.39) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL158581 | 0.85 | HPGD (0.50) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL16170747 | 0.85 | L3MBTL1 (0.35) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL7575059 | 0.85 | L3MBTL1 (0.35) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL16170509 | 0.85 | L3MBTL1 (0.35) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL4828988 | 0.82 | MAPT (0.49) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL16170453 | 0.82 | ELANE (0.42) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL26192623 | 0.82 | L3MBTL1 (0.33) | MAPTHPGDLMNA | |
| SCHEMBL26192574 | 0.82 | L3MBTL1 (0.33) | MAPTHPGDLMNA | |
| SCHEMBL16170572 | 0.82 | LMNA (0.42) | MAPTHPGDALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |