Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868301 | 0.98 | GAA (0.38) | GAAPOLBALDH1A1TSHRMAPT | |
| SCHEMBL3276196 | 0.98 | GAA (0.38) | GAAPOLBALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4542347 | 0.96 | GAA (0.37) | GAAPOLBALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL3337845 | 0.96 | GAA (0.37) | GAAPOLBALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4119676 | 0.78 | POLB (0.38) | GAAPOLBALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4248410 | 0.78 | HSP90AA1 (0.40) | GAAPOLBTRPM8HSP90AA1MAPK1 | |
| Hydrochloric Acid SCHEMBL175377 | 0.77 | POLB (0.37) | GAAPOLBALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4542337 | 0.77 | POLB (0.37) | GAAPOLBALDH1A1TSHRMAPT | |
| Iodide SCHEMBL2464728 | 0.77 | POLB (0.37) | GAAPOLBALDH1A1TSHRMAPT | |
| Bromide SCHEMBL2467102 | 0.77 | POLB (0.37) | GAAPOLBALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432694-A1 | STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF 2-YL CHROMAN DERIVATIVES | Wyeth (US) | 2004-06-30 | — | — | EP | disclosed |
| US-6716998-B2 | SUCH AS (2R)-3,4-DIHYDRO-2H-CHROMEN-2-YL-METHYL-4-METHYL-BENZENESULFONATE; METATHESIS RING CLOSING POLYMERIZATION | WYETH | 2004-04-06 | — | — | US | disclosed |
| WO-2003031428-A1 | STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF 2-YL CHROMAN DERIVATIVES | WYETH (US) | 2003-04-17 | — | — | WO | disclosed |